Teaching

BIOS 30415-01

Fundamental Neuroimmunology: Development, Communication, Breakdown

Together, we will dive into the nervous system to discover the hidden dialogue between the nervous and immune systems. This course moves beyond basic immunology to explore the complex and unique signaling of leukocytes, glia, and neurons – interactions found uniquely within the nervous system. In this evolving field, you won’t be just a passive observer; you will become an active investigator. In this course we will:

Deconstruct the players – Study the development and diverse functions of the nervous system’s specialized immune cells.

Decode the conversation – Explore how molecular signaling maintain health, or go awry during disease or injury.

Analyze the breakdown – Investigate the barriers that protect the central nervous system, why they fail, and cutting-edge therapies to target these systems during pathology.

WeekClass DateTopicGeneral Theme
114-JanCourse Intro and Spemann OrganizerTissue Organizing Centers I
221-JanHydra RegenerationTissue Organizing Centers II
328-JanPlanaria RegenerationStem Cells
44-FebLiver Regeneration in RodentsCell Proliferation and Cancer
511-FebMouse Digit Tip RegenerationFormation of a Blastema
618-FebZebrafish Fin RegenerationLineage Restriction
725-FebRetinal RegenerationDedifferentiation and Trans-differentiation
84-MarSalamander RegenerationPositional Identity
918-MarHeart Regeneration Across Species and AgesExtrinsic Environment – Fibrosis I
1025-MarAcomys RegenerationExtrinsic Environment – Fibrosis II
111-AprCNS vs. PNS RegenerationCell Extrinsic and Intrinsic Mechanisms
128-AprKillifish RegenerationCellular Aging and Extrinsic Environment
1315-AprAge-Dependent Spinal Cord RegenerationCellular Aging and Extrinsic Environment
1422-AprDeer Antler RegenerationIntegrating Concepts
1529-AprShark Tooth RegenerationIntegrating Concepts